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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
4.24
Human Site:
Y621
Identified Species:
9.33
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
Y621
L
L
S
G
V
V
A
Y
F
R
G
R
E
H
K
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
Y620
L
L
S
G
V
V
A
Y
F
R
G
R
E
R
K
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
V547
L
R
D
V
L
V
A
V
I
N
V
D
P
S
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
R621
I
I
A
W
V
V
A
R
F
R
N
R
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
R621
L
V
A
W
V
V
A
R
F
R
S
R
E
F
R
Chicken
Gallus gallus
XP_425053
1523
173782
I596
F
V
A
W
I
I
A
I
H
R
E
R
D
F
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
R492
L
D
Q
F
E
R
I
R
N
A
D
R
F
W
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
K590
G
A
G
Y
C
V
V
K
L
Q
N
S
K
R
R
Honey Bee
Apis mellifera
XP_624355
1492
172466
K604
G
A
G
Y
G
L
V
K
L
Q
N
R
R
R
R
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
N613
G
I
G
R
Y
L
V
N
R
R
I
A
I
G
H
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
H737
A
V
L
L
I
L
A
H
I
R
Q
H
S
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
93.3
20
N.A.
N.A.
N.A.
53.3
N.A.
53.3
26.6
N.A.
13.3
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
93.3
26.6
N.A.
N.A.
N.A.
73.3
N.A.
73.3
60
N.A.
13.3
N.A.
26.6
26.6
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
28
0
0
0
64
0
0
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
10
10
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
10
0
37
0
0
% E
% Phe:
10
0
0
10
0
0
0
0
37
0
0
0
10
19
10
% F
% Gly:
28
0
28
19
10
0
0
0
0
0
19
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
10
0
10
10
% H
% Ile:
10
19
0
0
19
10
10
10
19
0
10
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
0
0
10
0
37
% K
% Leu:
46
19
10
10
10
28
0
0
19
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
28
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
19
10
0
0
0
10
% Q
% Arg:
0
10
0
10
0
10
0
28
10
64
0
64
10
37
28
% R
% Ser:
0
0
19
0
0
0
0
0
0
0
10
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
28
0
10
37
55
28
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
28
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
19
10
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _